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Analysis of Group IV Viral SSHHPS Using In Vitro and In Silico Methods
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免疫学と感染
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JoVE Journal 免疫学と感染
Analysis of Group IV Viral SSHHPS Using In Vitro and In Silico Methods

Analysis of Group IV Viral SSHHPS Using In Vitro and In Silico Methods

25,714 Views

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10:40 min

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December 21, 2019

DOI:

10.3791/60421-v

DOI:
10.3791/60421-v

•

10:40 min
December 21, 2019

•

2 Views
, ,
1National Center for Advancing Translational Sciences,National Institutes of Health (NIH), 2United States Naval Research Laboratory

概要

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We present a general protocol for identifying short stretches of homologous host-pathogen protein sequences (SSHHPS) embedded in the viral polyprotein. SSHHPS are recognized by viral proteases and direct the targeted destruction of specific host proteins by several Group IV viruses.

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Cite this Article

Hu, X., Compton, J. R., Legler, P. M. Analysis of Group IV Viral SSHHPS Using In Vitro and In Silico Methods. J. Vis. Exp. (154), e60421, doi:10.3791/60421 (2019).

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