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Analysis of Group IV Viral SSHHPS Using In Vitro and In Silico Methods
JoVE Journal
Immunologia e infezioni
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JoVE Journal Immunologia e infezioni
Analysis of Group IV Viral SSHHPS Using In Vitro and In Silico Methods

Analysis of Group IV Viral SSHHPS Using In Vitro and In Silico Methods

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10:40 min

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December 21, 2019

DOI:

10.3791/60421-v

DOI:
10.3791/60421-v

•

10:40 min
December 21, 2019

•

2 Views
, ,
1National Center for Advancing Translational Sciences,National Institutes of Health, 2United States Naval Research Laboratory

Summary

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We present a general protocol for identifying short stretches of homologous host-pathogen protein sequences (SSHHPS) embedded in the viral polyprotein. SSHHPS are recognized by viral proteases and direct the targeted destruction of specific host proteins by several Group IV viruses.

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Cite this Article

Hu, X., Compton, J. R., Legler, P. M. Analysis of Group IV Viral SSHHPS Using In Vitro and In Silico Methods. J. Vis. Exp. (154), e60421, doi:10.3791/60421 (2019).

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