このコンテンツを視聴するには、JoVE 購読が必要です。 サインイン又は無料トライアルを申し込む。
In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila
13,327 Views
•
00:06 min
•
August 20, 2019
DOI:
1Department of Molecular and Human Genetics,Baylor College of Medicine, 2Program in Developmental Biology,Baylor College of Medicine, 3Department of Pediatrics, Section of Neurology and Developmental Neuroscience,Baylor College of Medicine, 4Jan and Dan Duncan Neurological Research Institute,Texas Children’s Hospital, 5神経科学科,Baylor College of Medicine
概要
Automatically generated
The goal of this protocol is to outline the design and performance of in vivo experiments in Drosophila melanogaster to assess the functional consequences of rare gene variants associated with human diseases.
Read Article
Cite this Article
Harnish, J. M., Deal, S. L., Chao, H., Wangler, M. F., Yamamoto, S. In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila. J. Vis. Exp. (150), e59658, doi:10.3791/59658 (2019).
Copy