A Standardized Method for Measuring Internal Lung Surface Area via Mouse Pneumonectomy and Prosthesis Implantation

Zhe Liu; Siling Fu; Nan Tang

doi:10.3791/56114

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発生生物学

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A Standardized Method for Measuring Internal Lung Surface Area via Mouse Pneumonectomy and Prosthesis Implantation

JoVE Journal
発生生物学

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JoVE Journal 発生生物学

A Standardized Method for Measuring Internal Lung Surface Area via Mouse Pneumonectomy and Prosthesis Implantation

12,839 Views

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08:46 min

•

July 26, 2017

DOI:

10.3791/56114-v

DOI:

10.3791/56114-v

•

08:46 min

July 26, 2017

•

6 Views

Zhe Liu^1,2, Siling Fu^2,3, Nan Tang²

¹Department of Life Sciences,Peking University, ²National Institute of Biological Sciences, Beijing, ³Graduate School of Peking Union Medical College

概要

Internal lung surface area (ISA) is a critical criterion for assessing lung morphology and physiology in lung diseases and injury-induced alveolar regeneration. We describe here a standardized method that can minimize the measurement bias for ISA in both lung pneumonectomy and prosthesis implantation mouse models.

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Keyword Extraction:Mouse Pneumonectomy Prosthesis Implantation Internal Lung Surface Area Lung Function Mechanical Force-induced Adult Lung Regeneration Tracheal Intubation Thoracotomy Left Lung Lobe Removal Pulmonary Artery And Bronchi Ligation Chest Wall Closure Post-operative Care

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A Standardized Method for Measuring Internal Lung Surface Area via Mouse Pneumonectomy and Prosthesis Implantation

概要

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