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Una piattaforma di test anti-biofilm Adatto per l'esplorazione del Biblioteche composto naturale
JoVE Journal
免疫学と感染
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JoVE Journal 免疫学と感染
A Platform of Anti-biofilm Assays Suited to the Exploration of Natural Compound Libraries

Una piattaforma di test anti-biofilm Adatto per l'esplorazione del Biblioteche composto naturale

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09:39 min

December 27, 2016

DOI:

09:39 min
December 27, 2016

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概要

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Biofilm infections show high tolerance towards chemotherapy. No single assay captures the complexity of biofilms. Instead, complementary assays are needed. We present a screening platform (developed for S. aureus) that combines assays for viability, biomass, and biofilm matrix. It allows anti-biofilm drug discovery, including the assessment of long-term chemotherapeutic effects.

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