需要订阅 JoVE 才能查看此. 登录或开始免费试用。
A Platform of Anti-biofilm Assays Suited to the Exploration of Natural Compound Libraries
17,095 Views
•
09:39 min
•
December 27, 2016
DOI:
Summary
Automatically generated
Biofilm infections show high tolerance towards chemotherapy. No single assay captures the complexity of biofilms. Instead, complementary assays are needed. We present a screening platform (developed for S. aureus) that combines assays for viability, biomass, and biofilm matrix. It allows anti-biofilm drug discovery, including the assessment of long-term chemotherapeutic effects.
Read Article
Cite this Article
Skogman, M. E., Vuorela, P. M., Fallarero, A. A Platform of Anti-biofilm Assays Suited to the Exploration of Natural Compound Libraries. J. Vis. Exp. (118), e54829, doi:10.3791/54829 (2016).
Copy