Measuring Ascending Aortic Stiffness In Vivo in Mice Using Ultrasound

Maggie M. Kuo; Viachaslau Barodka; Theodore P. Abraham; Jochen Steppan; Artin A. Shoukas; Mark Butlin; Alberto Avolio; Dan E. Berkowitz; Lakshmi Santhanam

doi:10.3791/52200

ジャーナル

/

医学

/

מדידה עולה אבי העורקים נוקשים In vivo בעכברים באמצעות אולטראסאונד

JoVE Journal
医学

This content is Free Access.

JoVE Journal 医学

Measuring Ascending Aortic Stiffness In Vivo in Mice Using Ultrasound

Please note that all translations are automatically generated. Click here for the English version.

מדידה עולה אבי העורקים נוקשים In vivo בעכברים באמצעות אולטראסאונד

15,757 Views

•

10:08 min

•

December 02, 2014

DOI:

10.3791/52200-v

DOI:

10.3791/52200-v

•

10:08 min

December 02, 2014

•

11 Views

Maggie M. Kuo¹, Viachaslau Barodka², Theodore P. Abraham³, Jochen Steppan², Artin A. Shoukas¹, Mark Butlin⁴, Alberto Avolio⁴, Dan E. Berkowitz^1,2, Lakshmi Santhanam^1,2

¹Department of Biomedical Engineering,Johns Hopkins University, ²Department of Anesthesiology and Critical Care Medicine,Johns Hopkins University, ³Department of Medicine (Cardiology),Johns Hopkins University, ⁴The Australian School of Advanced Medicine,Macquarie University

概要

We describe a technique for measuring aortic stiffness from its pressure-diameter relationship in vivo in mice. Aortic diameter is recorded by ultrasound and aortic pressure is measured invasively with a solid-state pressure catheter. Blood pressure is changed incrementally and the resulting diameter is measured.

Explore More Videos

Aortic Stiffness In Vivo Mice Ultrasound Pressure-diameter Relationship Arterial Compliance Cardiovascular Disease Aging Vasoactive Drugs Phenylephrine Sodium Nitroprusside Aortic Diameter Aortic Blood Pressure

Read Article

מדידה עולה אבי העורקים נוקשים<em> In vivo</em> בעכברים באמצעות אולטראסאונד

概要

Automatically generated

Explore More Videos