A Simple Protocol for Platelet-mediated Clumping of <em>Plasmodium falciparum</em>-infected Erythrocytes in a Resource Poor Setting

Dumizulu L. Tembo; Jacqui Montgomery; Alister G. Craig; Samuel C. Wassmer

doi:10.3791/4316

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A Simple Protocol for Platelet-mediated Clumping of Plasmodium falciparum-infected Erythrocytes in a Resource Poor Setting

JoVE Journal
免疫学と感染

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JoVE Journal 免疫学と感染

A Simple Protocol for Platelet-mediated Clumping of Plasmodium falciparum-infected Erythrocytes in a Resource Poor Setting

A Simple Protocol for Platelet-mediated Clumping of Plasmodium falciparum-infected Erythrocytes in a Resource Poor Setting

18,448 Views

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07:27 min

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May 16, 2013

DOI:

10.3791/4316-v

DOI:

10.3791/4316-v

•

07:27 min

May 16, 2013

•

3 Views

Dumizulu L. Tembo¹, Jacqui Montgomery¹, Alister G. Craig², Samuel C. Wassmer³

¹Malawi-Liverpool-Wellcome Trust Clinical Research Programme, ²Liverpool School of Tropical Medicine, ³Department of Microbiology, Division of Medical Parasitology,New York University School of Medicine

概要

This method investigates the platelet-mediated clumping phenotype of Plasmodium falciparum-infected erythrocytes (pRBC) in clinical isolates. This is performed by isolating and co-incubating platelet-rich plasma and a suspension of pRBC.

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A Simple Protocol for Platelet-mediated Clumping of Plasmodium falciparum-infected Erythrocytes in a Resource Poor Setting

概要

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