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Biomarker 디스커버리를위한 Mesoporous 실리카 박막의 낮은 분자량의 단백질 농축
JoVE Journal
生物工学
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JoVE Journal 生物工学
Low Molecular Weight Protein Enrichment on Mesoporous Silica Thin Films for Biomarker Discovery
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Biomarker 디스커버리를위한 Mesoporous 실리카 박막의 낮은 분자량의 단백질 농축

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13:00 min

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April 17, 2012

DOI:

10.3791/3876-v

DOI:
10.3791/3876-v

•

13:00 min
April 17, 2012

•

1 Views
, , , , , ,
1Department of Nanomedicine,The Methodist Hospital Research Institute, 2CAS Key Laboratory for Biological Effects of Nanomaterials & Nanosafety,National Center for Nanoscience and Technology

概要

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우리는 인간의 혈청에서 낮은 분자량의 단백질과 펩티드의 선택적 회수를위한 mesoporous 실리카 박막을 기반으로 기술을 개발했습니다. 우리 mesoporous 칩 physico - 화학적 성질은 잘게 펩타이드 강화에 실질적인 컨트롤을 제공하며, 결과적으로 진단을 위해 혈청 프로테옴을 프로파일하기 위해 조정되었습니다.

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Cite this Article

Fan, J., Gallagher, J. W., Wu, H., Landry, M. G., Sakamoto, J., Ferrari, M., Hu, Y. Low Molecular Weight Protein Enrichment on Mesoporous Silica Thin Films for Biomarker Discovery. J. Vis. Exp. (62), e3876, doi:10.3791/3876 (2012).

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