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Basophil Activation Test for Investigation of IgE-Mediated Mechanisms in Drug Hypersensitivity
JoVE Journal
免疫学と感染
This content is Free Access.
JoVE Journal 免疫学と感染
Basophil Activation Test for Investigation of IgE-Mediated Mechanisms in Drug Hypersensitivity

Basophil Activation Test for Investigation of IgE-Mediated Mechanisms in Drug Hypersensitivity

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10:22 min

September 16, 2011

DOI:

10:22 min
September 16, 2011

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概要

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Basophil activation test is a potent tool for the detection of IgE-dependent allergies in vitro. Here, an optimized protocol for basophil activation test is used to investigate drug hypersensitivity. A method for the efficient production of covalent drug-protein conjugates and their physicochemical characterization is described.

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