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Detection of Neuritic Plaques in Alzheimer’s Disease Mouse Model
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July 26, 2011
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One of the pathological characteristics of AD is the formation of Amyloid β protein positive neuritic plaques. In this protocol we describe two methods to detect neuritic plaques in transgenic AD model mice: immunohistochemical detection using the ABC and DAB method and fluorescent detection using thioflavin S staining method.
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Ly, P. T., Cai, F., Song, W. Detection of Neuritic Plaques in Alzheimer's Disease Mouse Model. J. Vis. Exp. (53), e2831, doi:10.3791/2831 (2011).
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