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Using Bioluminescent Imaging to Investigate Synergism Between Streptococcus pneumoniae and Influenza A Virus in Infant Mice
JoVE Journal
免疫学と感染
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JoVE Journal 免疫学と感染
Using Bioluminescent Imaging to Investigate Synergism Between Streptococcus pneumoniae and Influenza A Virus in Infant Mice

Using Bioluminescent Imaging to Investigate Synergism Between Streptococcus pneumoniae and Influenza A Virus in Infant Mice

16,537 Views

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10:47 min

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April 14, 2011

DOI:

10.3791/2357-v

DOI:
10.3791/2357-v

•

10:47 min
April 14, 2011

•

3 Views
, , , , , ,
1Department of Microbiology and Immunology,University of Melbourne, 2Laboratory of Pediatric Infectious Diseases,Radboud University Nijmegen Medical Centre, 3The Centre for Dynamic Imaging,The Walter and Eliza Hall Institute for Medical Research

概要

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A concurrent infection with influenza A virus is one of the factors implicated in the induction of invasive pneumococcal disease during asymptomatic Streptococcus pneumoniae carriage. Here we describe a mixed infection method using infant mice to investigate the synergism between these two respiratory pathogens.

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Short, K. R., Diavatopoulos, D. A., Reading, P. C., Brown, L. E., Rogers, K. L., Strugnell, R. A., Wijburg, O. L. Using Bioluminescent Imaging to Investigate Synergism Between Streptococcus pneumoniae and Influenza A Virus in Infant Mice. J. Vis. Exp. (50), e2357, doi:10.3791/2357 (2011).

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