JOVE JOURNAL

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Showing 313 - 324 in 611 videos.

Assessing Cellular Target Engagement by SHP2 (PTPN11) Phosphatase Inhibitors

Lester J. Lambert¹, Celeste Romero¹, Douglas J. Sheffler¹, Maria Celeridad¹, Nicholas D. P. Cosford¹, Lutz Tautz¹

¹Cancer Metabolism & Signaling Networks Program, NCI-Designated Cancer Center,Sanford Burnham Prebys Medical Discovery Institute

Journal (Cancer Research)

Mapping the Structure-Function Relationships of Disordered Oncogenic Transcription Factors Using Transcriptomic Analysis

Iftekhar A. Showpnil^1,2, Kyle R. Miller¹, Cenny Taslim¹, Kathleen I. Pishas¹, Stephen L. Lessnick^1,3, Emily R. Theisen^1,4

¹Center for Childhood Cancer and Blood Diseases,Abigail Wexner Research Institute at Nationwide Children's Hospital, ²Molecular, Cellular, and Developmental Biology Program,The Ohio State University, ³Division of Pediatric Hematology/Oncology/Blood & Marrow Transplant,The Ohio State University, ⁴小児科,The Ohio State University

Journal (Cancer Research)

Monitoring Cancer Cell Invasion and T-Cell Cytotoxicity in 3D Culture

Yuan-Na Lin¹, Apsra Nasir¹, Sharon Camacho¹, Deborah L. Berry¹, Marcel O. Schmidt¹, Gray W. Pearson¹, Anna T. Riegel¹, Anton Wellstein¹

¹Lombardi Comprehensive Cancer Center, Department of Oncology,Georgetown University

Journal (Cancer Research)

Evaluating Cell Death Using Cell-Free Supernatant of Probiotics in Three-Dimensional Spheroid Cultures of Colorectal Cancer Cells

Jina Lee*^1,2, Joo-Eun Lee*³, Seil Kim^1,4,5, Dukjin Kang¹, Hee Min Yoo¹

¹Microbiological Analysis Team, Group for Biometrology,Korea Research Institute of Standards and Science (KRISS), ²College of Pharmacy,Chungnam National University (CNU), ³Stem Cell Research Center,Korea Research Institute of Bioscience and Biotechnology (KRIBB), ⁴Convergent Research Center for Emerging Virus Infection,Korea Research Institute of Chemical Technology (KRICT), ⁵Department of Bio-Analysis Science,University of Science & Technology (UST)

Journal (Cancer Research)

Immunofluorescence Imaging of DNA Damage and Repair Foci in Human Colon Cancer Cells

Kamila Maliszewska-Olejniczak¹, Agnieszka Dróżdż¹, Martyna Waluś¹, Michał Dorosz¹, Michał A. Gryziński¹

¹Nuclear Facilities Operations Department,National Centre for Nuclear Research, Sołtana 7, 05-400 Otwock, Poland

Journal (Cancer Research)

Evaluation of Colorectal Cancer Risk and Prevalence by Stool DNA Integrity Detection

Claudia Rengucci¹, Giulia De Maio¹, Maura Menghi², Francesca Benzi², Daniele Calistri¹

¹Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, Meldola, Italy, ²Diatech Pharmacogenetics srl

Journal (Cancer Research)

Modeling Brain Metastases Through Intracranial Injection and Magnetic Resonance Imaging

Jennifer A. Geisler^1,2,3, Jonathan M. Spehar^1,2, Sarah A. Steck^1,2, Anna Bratasz^1,4, Reena Shakya¹, Kimerly Powell^1,4, Gina M. Sizemore^1,2

¹The Comprehensive Cancer Center,The Ohio State University, ²放射線腫瘍学科,The Ohio State University, ³Department of Veterinary Biosciences,The Ohio State University, ⁴Davis Heart & Lung Research Institute,The Ohio State University

Journal (Cancer Research)

Pathological Analysis of Lung Metastasis Following Lateral Tail-Vein Injection of Tumor Cells

Katie A Thies¹, Sarah Steck¹, Sue E Knoblaugh², Steven T Sizemore¹

¹Department of Radiation Oncology, Arthur G. James Comprehensive Cancer Center and Richard L. Solove Research Institute,The Ohio State University Medical Center, ²Department of Veterinary Biosciences, Comparative Pathology and Digital Imaging Shared Resource,The Ohio State University

Journal (Cancer Research)

Orthotopic Transplantation of Breast Tumors as Preclinical Models for Breast Cancer

Xiangdong Lv*^1,2,3, Lacey E. Dobrolecki*^1,2,3, Yao Ding^1,2,3, Jeffrey M. Rosen^1,2,3, Michael T. Lewis^1,2,3, Xi Chen^1,2,3

¹Department of Molecular and Cellular Biology,Baylor College of Medicine, ²Lester and Sue Smith Breast Center,Baylor College of Medicine, ³Dan L. Duncan Cancer Center,Baylor College of Medicine

Journal (Cancer Research)

Analyzing Tumor and Tissue Distribution of Target Antigen Specific Therapeutic Antibody

Gururaj Shivange*^1,2, Tanmoy Mondal*^1,2, Evan Lyerly^1,2, Jeremy Gatesman³, Jogender Tushir-Singh^1,2

¹Laboratory of Novel Biologics,University of Virginia School of Medicine, ²Department of Biochemistry and Molecular Genetics, UVA Cancer Center,University of Virginia School of Medicine, ³Center for Comparative Medicine,University of Virginia

Journal (Cancer Research)

An Automated Differential Nuclear Staining Assay for Accurate Determination of Mitocan Cytotoxicity

Jingqi Pei*¹, Svetlana B. Panina*¹, Natalia V. Kirienko¹

¹Department of BioSciences,Rice University

Journal (Cancer Research)

Combined Conditional Knockdown and Adapted Sphere Formation Assay to Study a Stemness-Associated Gene of Patient-derived Gastric Cancer Stem Cells

Jixian Xiong*¹, Yuting Li*¹, Xiangyu Tan*¹, Li Fu¹

¹Guangdong Key Laboratory of Genome Stability and Human Disease Prevention, Department of Pharmacology and Shenzhen University International Cancer Center,Shenzhen University School of Medicine

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