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A Procedure to Study Stress-Induced Relapse of Heroin Seeking after Punishment-Imposed Abstinence
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Capitoli
- 00:04Introduction
- 00:43Behavioral Procedure
- 06:39Results: Acute Food Deprivation-Induced Relapse to Heroin Seeking Abstinence in the Rats
- 07:27Conclusion
A procedure that demonstrates a robust acute food deprivation-induced relapse to heroin seeking after punishment-imposed abstinence is described. A punishment-imposed abstinence model was successfully implemented using the seek and take chain schedule for heroin self-administration. Heroin-seeking tests are then performed following 24 h of food-deprivation stress.
