The present protocol describes a single-cell method for iterative epigenomic analyses using a reusable single cell. The reusable single cell allows analyses of multiple epigenetic marks in the same single cell and statistical validation of the results.
Ohnuki, H., Venzon, D. J., Lobanov, A., Tosato, G. Reusable Single Cell for Iterative Epigenomic Analyses. J. Vis. Exp. (180), e63456, doi:10.3791/63456 (2022).