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Analysis of Liver Microenvironment During Early Progression of Non-Alcoholic Fatty Liver Disease-Associated Hepatocellular Carcinoma in Zebrafish
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Analysis of Liver Microenvironment During Early Progression of Non-Alcoholic Fatty Liver Disease-Associated Hepatocellular Carcinoma in Zebrafish
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09:27 min
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April 01, 2021
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1Department of Developmental and Molecular Biology,Albert Einstein College of Medicine, 2Department of Medicine (Hepatology),Albert Einstein College of Medicine, 3Einstein-Mount Sinai Diabetes Research Center,Albert Einstein College of Medicine, 4Marion Bessin Liver Research Center,Albert Einstein College of Medicine
Summary
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Here, we present how to generate a non-alcoholic fatty liver disease (NAFLD)-associated Hepatocellular Carcinoma (HCC) zebrafish model to study the impact of cholesterol surplus on liver microenvironment and immune cell landscape.
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Michael, C., Martínez-Navarro, F. J., de Oliveira, S. Analysis of Liver Microenvironment During Early Progression of Non-Alcoholic Fatty Liver Disease-Associated Hepatocellular Carcinoma in Zebrafish. J. Vis. Exp. (170), e62457, doi:10.3791/62457 (2021).
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