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Quantitative Measurement of Intrathecally Synthesized Proteins in Mice
JoVE Journal
Neuroscienze
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JoVE Journal Neuroscienze
Quantitative Measurement of Intrathecally Synthesized Proteins in Mice

Quantitative Measurement of Intrathecally Synthesized Proteins in Mice

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08:23 min

November 29, 2019

DOI:

08:23 min
November 29, 2019

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Summary

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Elevated spinal fluid protein levels can either be the result of diffusion of plasma protein across an altered blood-brain barrier or intrathecal synthesis. An optimized testing protocol is presented in this article that helps to discriminate both cases and provides quantitative measurements of intrathecally synthesized proteins.

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