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Análisis de SSHHPS Viral del Grupo IV utilizando métodos In Vitro y In Silico
JoVE Journal
Immunologia e infezioni
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JoVE Journal Immunologia e infezioni
Analysis of Group IV Viral SSHHPS Using In Vitro and In Silico Methods
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Análisis de SSHHPS Viral del Grupo IV utilizando métodos In Vitro y In Silico

25,692 Views

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10:40 min

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December 21, 2019

DOI:

10.3791/60421-v

DOI:
10.3791/60421-v

•

10:40 min
December 21, 2019

•

2 Views
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1National Center for Advancing Translational Sciences,National Institutes of Health, 2United States Naval Research Laboratory

Summary

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Presentamos un protocolo general para identificar tramos cortos de secuencias de proteínas homolopégicos de patógenos de host (SSHHPS) incrustadas en la poliproteína viral. SSHHPS son reconocidos por proteasas virales y dirigen la destrucción dirigida de proteínas huésped específicas por varios virus del Grupo IV.

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Cite this Article

Hu, X., Compton, J. R., Legler, P. M. Analysis of Group IV Viral SSHHPS Using In Vitro and In Silico Methods. J. Vis. Exp. (154), e60421, doi:10.3791/60421 (2019).

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