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联合药物输液和电生理学的显微注射系统

JoVE Journal
Neuroscienze

This content is Free Access.

JoVE Journal Neuroscienze

Microinjectrode System for Combined Drug Infusion and Electrophysiology

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联合药物输液和电生理学的显微注射系统

6,462 Views

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08:30 min

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November 13, 2019

DOI:

10.3791/60365-v

DOI:

10.3791/60365-v

•

08:30 min

November 13, 2019

•

1 Views

M. Isabel Vanegas¹, Kenneth R. Hubbard^1,2, Rahim Esfandyarpour^3,4, Behrad Noudoost¹

¹Department of Ophthalmology and Visual Sciences,University of Utah, ²Department of Biomedical Engineering,University of Utah, ³Department of Electrical Engineering and Computer Science,University of California, Irvine, ⁴Department of Biomedical Engineering,University of California, Irvine

Summary

我们提出了一个显微注射系统，用于电生理学和辅助交付实验探头（即纳米传感器，微电极），可选配药物输注。广泛可用的微流体成分与包含探头的导管耦合。包括一个微注射的分步协议，在猴皮层中注入木糖醇时的结果。

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