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利用人类诱导多能干细胞生成肿瘤抗原特异性T细胞
JoVE Journal
Ricerca sul cancro
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JoVE Journal Ricerca sul cancro
Using Human Induced Pluripotent Stem Cells for the Generation of Tumor Antigen-specific T Cells
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利用人类诱导多能干细胞生成肿瘤抗原特异性T细胞

9,859 Views

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10:57 min

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October 24, 2019

DOI:

10.3791/59997-v

DOI:
10.3791/59997-v

•

10:57 min
October 24, 2019

•

5 Views
, , , , , ,
1Surgery Branch,National Cancer Institute, NIH, 2Center for Cell-Based Therapy,National Cancer Institute, NIH, 3Laboratory of Immunology, Institute for Frontier Life and Medical Sciences,Kyoto University

Summary

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本文介绍了一种利用OP9/DLL1共培养系统生成功能性肿瘤抗原特异性诱导多能干细胞衍生CD8++单阳性T细胞的方法。

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Cite this Article

Good, M. L., Vizcardo, R., Maeda, T., Tamaoki, N., Malekzadeh, P., Kawamoto, H., Restifo, N. P. Using Human Induced Pluripotent Stem Cells for the Generation of Tumor Antigen-specific T Cells. J. Vis. Exp. (152), e59997, doi:10.3791/59997 (2019).

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