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Characterizing Mutational Load and Clonal Composition of Human Blood
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July 11, 2019
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Somatic mutation patterns in cells reflect previous mutagenic exposure and can reveal developmental lineage relationships. Presented here is a methodology to catalogue and analyze somatic mutations in individual hematopoietic stem and progenitor cells.
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Huber, A. R., Manders, F., Oka, R., van Boxtel, R. Characterizing Mutational Load and Clonal Composition of Human Blood. J. Vis. Exp. (149), e59846, doi:10.3791/59846 (2019).
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