Megakaryocyte Differentiation and Platelet Formation from Human Cord Blood-derived CD34<sup>+</sup> Cells

Jose Perdomo; Feng Yan; Halina H.L. Leung; Beng H. Chong

doi:10.3791/56420

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Immunologia e infezioni

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Megakaryocyte Differentiation and Platelet Formation from Human Cord Blood-derived CD34⁺ Cells

JoVE Journal
Immunologia e infezioni

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JoVE Journal Immunologia e infezioni

Megakaryocyte Differentiation and Platelet Formation from Human Cord Blood-derived CD34⁺ Cells

19,162 Views

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09:46 min

•

December 27, 2017

DOI:

10.3791/56420-v

DOI:

10.3791/56420-v

•

09:46 min

December 27, 2017

•

17 Views

Jose Perdomo¹, Feng Yan¹, Halina H.L. Leung¹, Beng H. Chong^1,2

¹Haematology Research Unit, St George and Sutherland Clinical School,University of New South Wales, ²Haematology Department,St George and Sutherland Hospitals

Summary

A highly pure population of megakaryocytes can be obtained from cord blood-derived CD34⁺ cells. A method for CD34⁺cell isolation and megakaryocyte differentiation is described here.

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Megakaryocyte Differentiation and Platelet Formation from Human Cord Blood-derived CD34+ Cells

Summary

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Megakaryocyte Differentiation and Platelet Formation from Human Cord Blood-derived CD34⁺ Cells