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Гепатоцитов конкретных абляция в данио рерио по изучению желчных приводом печени Регенерация
JoVE Journal
Biologia dello sviluppo
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JoVE Journal Biologia dello sviluppo
Hepatocyte-specific Ablation in Zebrafish to Study Biliary-driven Liver Regeneration

Гепатоцитов конкретных абляция в данио рерио по изучению желчных приводом печени Регенерация

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08:14 min

May 20, 2015

DOI:

08:14 min
May 20, 2015

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Summary

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To help assess the molecular mechanisms underlying zebrafish biliary-driven liver regeneration, we established a liver injury model in which the nitroreductase-expressing hepatocytes are genetically ablated upon metronidazole treatment. In this protocol, we describe how to adeptly manipulate, monitor and analyze hepatocyte ablation and biliary-driven liver regeneration.

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