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Applying Stereotactic Injection Technique to Study Genetic Effects on Animal Behaviors
JoVE Journal
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Applying Stereotactic Injection Technique to Study Genetic Effects on Animal Behaviors

Applying Stereotactic Injection Technique to Study Genetic Effects on Animal Behaviors

13,945 Views

07:54 min

May 10, 2015

DOI:

07:54 min
May 10, 2015

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Summary

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Stereotactic injection of lentiviruses expressing cDNAs or shRNAs can modulate gene expression in specific brain areas of mice. Here, we present a protocol to combine stereotactic injections with behavioral tasks, such as the Open Field Test (OFT) and the Forced Swim Test (FST).

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