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Applying Stereotactic Injection Technique to Study Genetic Effects on Animal Behaviors
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May 10, 2015
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Stereotactic injection of lentiviruses expressing cDNAs or shRNAs can modulate gene expression in specific brain areas of mice. Here, we present a protocol to combine stereotactic injections with behavioral tasks, such as the Open Field Test (OFT) and the Forced Swim Test (FST).
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McSweeney, C., Mao, Y. Applying Stereotactic Injection Technique to Study Genetic Effects on Animal Behaviors. J. Vis. Exp. (99), e52653, doi:10.3791/52653 (2015).
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