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쥐에서 초음파 기술을 사용하여 약물 유발 신장 혈역학 적 부전의 조기 발견
JoVE Journal
Medicina
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JoVE Journal Medicina
Early Detection of Drug-Induced Renal Hemodynamic Dysfunction Using Sonographic Technology in Rats
Please note that all translations are automatically generated. Click here for the English version.

쥐에서 초음파 기술을 사용하여 약물 유발 신장 혈역학 적 부전의 조기 발견

11,638 Views

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06:38 min

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March 11, 2016

DOI:

10.3791/52409-v

DOI:
10.3791/52409-v

•

06:38 min
March 11, 2016

•

3 Views
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1Cardiac Muscle Research Laboratory, Cardiovascular Division,Brigham and Women’s Hospital, Harvard Medical School, 2Renal Division,Brigham and Women’s Hospital, Harvard Medical School

Summary

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Early stage hemodynamic dysfunction is critical to the development of kidney disease. Yet, detection methodologies are limited. Recent advances in sonography provide a noninvasive, accurate option for early detection of kidney injury. This study outlines a step-by-step, sonographic methodology for detecting kidney dysfunction using a drug-induced nephrotoxicity rat model.

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Fisch, S., Liao, R., Hsiao, L., Lu, T. Early Detection of Drug-Induced Renal Hemodynamic Dysfunction Using Sonographic Technology in Rats. J. Vis. Exp. (109), e52409, doi:10.3791/52409 (2016).

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