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Farelerde Nöropatik Ağrı Siyatik Sinir cuffing Modeli
JoVE Journal
Medicina
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JoVE Journal Medicina
The Sciatic Nerve Cuffing Model of Neuropathic Pain in Mice
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Farelerde Nöropatik Ağrı Siyatik Sinir cuffing Modeli

47,197 Views

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07:09 min

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July 16, 2014

DOI:

10.3791/51608-v

DOI:
10.3791/51608-v

•

07:09 min
July 16, 2014

•

64 Views
, , , , , ,
1Institut des Neurosciences Cellulaires et Intégratives UPR3212,Centre National de la Recherche Scientifique, 2Université de Strasbourg, 3Hôpitaux Universitaires de Strasbourg

Summary

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Nöropatik ağrı somatosensory sistemini etkileyen bir yara ya da hastalık, bir sonucudur. Farelerde nöropatik ağrı "ağzı model" siyatik sinirin ana dal etrafında bir polietilen manşetin implantasyon oluşur. Mekanik alodinia von Frey filamentleri kullanılarak test edilir.

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Cite this Article

Yalcin, I., Megat, S., Barthas, F., Waltisperger, E., Kremer, M., Salvat, E., Barrot, M. The Sciatic Nerve Cuffing Model of Neuropathic Pain in Mice. J. Vis. Exp. (89), e51608, doi:10.3791/51608 (2014).

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