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鼠标型号病原体引起的慢性炎症局部及全身站点
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Immunologia e infezioni
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JoVE Journal Immunologia e infezioni
A Mouse Model for Pathogen-induced Chronic Inflammation at Local and Systemic Sites
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鼠标型号病原体引起的慢性炎症局部及全身站点

DOI:
10.3791/51556-v

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09:52 min

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August 08, 2014

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, , , , , , ,
1Department of Medicine, Section of Infectious Disease,Boston University School of Medicine, 2Department of Biophysics,Boston University School of Medicine

Capitoli

  • 00:05Titolo
  • 01:55Growth and Cultivation of Bacteria
  • 03:25MRI Data Acquisition
  • 05:00Aorta Pinning
  • 06:07Lipid Staining and Lesion Quantification
  • 07:27Results: Pathogen-induced Chronic Inflammation at Local and Systemic Sites
  • 08:52Conclusion

Summary

Traduzione automatica

Traduzione automatica

动物模型中已被证明是在界定有助于慢性炎症的发展宿主和病原体的具体机制的宝贵工具。在这里，我们描述口腔感染的小鼠模型与人类病原体牙龈卟啉和细节的方法，以评估炎症的进展，在局部和全身的部位。

Tags

Mouse ModelChronic InflammationPathogen-inducedPorphyromonas GingivalisPeriodontal DiseaseAtherosclerosisInflammatory ResponseAlveolar BoneVascular EndotheliumInflammatory MediatorsTransgenic MiceBacterial MutantsTherapeutic Strategies

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