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Controlling Parkinson’s Disease With Adaptive Deep Brain Stimulation
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JoVE Journal Medicina
Controlling Parkinson’s Disease With Adaptive Deep Brain Stimulation

Controlling Parkinson’s Disease With Adaptive Deep Brain Stimulation

21,798 Views

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11:12 min

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July 16, 2014

DOI:

10.3791/51403-v

DOI:
10.3791/51403-v

•

11:12 min
July 16, 2014

•

11 Views
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1Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital,University of Oxford, 2Sobell Department of Motor Neuroscience & Movement Disorders, Unit of Functional Neurosurgery,UCL Institute of Neurology

Summary

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Adaptive deep brain stimulation (aDBS) is effective for Parkinson’s disease, improving symptoms and reducing power consumption compared to conventional deep brain stimulation (cDBS). In aDBS we track a local field potential biomarker (beta oscillatory amplitude) in real time and use this to control the timing of stimulation.

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Parkinson’s DiseaseAdaptive Deep Brain StimulationADBSSubthalamic NucleusBeta AmplitudeReal-time OptimizationMotor FunctionUPDRSPower ConsumptionChronic Stimulation

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Cite this Article

Little, S., Pogosyan, A., Neal, S., Zrinzo, L., Hariz, M., Foltynie, T., Limousin, P., Brown, P. Controlling Parkinson's Disease With Adaptive Deep Brain Stimulation. J. Vis. Exp. (89), e51403, doi:10.3791/51403 (2014).

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