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使用超声波血脑屏障破坏和锰增强MRI的脑功能成像

JoVE Journal
Neuroscienze

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JoVE Journal Neuroscienze

Functional Neuroimaging Using Ultrasonic Blood-brain Barrier Disruption and Manganese-enhanced MRI

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使用超声波血脑屏障破坏和锰增强MRI的脑功能成像

14,830 Views

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08:36 min

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July 12, 2012

DOI:

DOI:

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08:36 min

July 12, 2012

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2 Views

Gabriel P. Howles¹, Yi Qi², Stephen J. Rosenzweig³, Kathryn R. Nightingale³, G. Allan Johnson²

¹Department of Radiology,Stanford University , ²Center for In Vivo Microscopy,Duke University Medical Center, ³Department of Biomedical Engineering,Duke University

Summary

一个被描述为广泛的开放血脑屏障在鼠标使用微泡和超声技术。使用这种技术，锰，可管理的鼠脑。因为锰是一个磁共振造影剂，在去极化神经元的积累，这种方法能够使神经元的活动影像。

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