This content is Free Access.
Monitoring Tumor Metastases and Osteolytic Lesions with Bioluminescence and Micro CT Imaging
24,336 Views
•
08:04 min
•
April 14, 2011
DOI:
Summary
Automatically generated
An experimental mouse model of bone metastasis was established following intracardiac delivery of luciferase expressing mammary tumor cells. Tumor development and resulted osteolytic lesion were monitored longitudinally with bioluminescence and micro CT imaging.
Explore More Videos
Tumor MetastasesOsteolytic LesionsBioluminescence ImagingMicro CT ImagingMDA-MB-231-luc-D3H2LN CellsNu/Nu MiceIntracardiac DeliverySystemic MetastasesIVIS SpectrumDLIT ReconstructionTumor SignalTibiaFemurMicro CT SystemQuantum FXX-ray DoseRadiation DoseLD50Mouse Imaging Shuttle DeviceAnimal PositioningCo-registrationLiving Image 4.1 Software
Read Article
Cite this Article
Lim, E., Modi, K., Christensen, A., Meganck, J., Oldfield, S., Zhang, N. Monitoring Tumor Metastases and Osteolytic Lesions with Bioluminescence and Micro CT Imaging. J. Vis. Exp. (50), e2775, doi:10.3791/2775 (2011).
Copy