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An Optic Nerve Crush Injury Murine Model to Study Retinal Ganglion Cell Survival
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An Optic Nerve Crush Injury Murine Model to Study Retinal Ganglion Cell Survival
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April 25, 2011
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This protocol shows how to retrogradely label retinal ganglion cells, and how to subsequently make an optic nerve crush injury in order to analyze retinal ganglion cell survival and apoptosis. It is an experimental disease model for different types of optic neuropathy, including glaucoma.
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Tang, Z., Zhang, S., Lee, C., Kumar, A., Arjunan, P., Li, Y., Zhang, F., Li, X. An Optic Nerve Crush Injury Murine Model to Study Retinal Ganglion Cell Survival. J. Vis. Exp. (50), e2685, doi:10.3791/2685 (2011).
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