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랜덤 DNA 라이브러리를 사용하여 뇌관 - 무료 Aptamer 선택
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July 26, 2010
DOI:
1Department of Pathology, Hershey Medical Center,Pennsylvania State University, 2Department of Chemistry,Pennsylvania State University, 3Departments of Pathology, and Biochemistry and Molecular Biology, Hershey Medical Center,Pennsylvania State University, 4Materials Research Institute,Pennsylvania State University
Tags
Primer-Free Aptamer SelectionRandom DNA LibraryAptamersOligonucleotidesDNARNAAffinitiesAntibodiesIn Vitro Selection ProcessSystematic Evolution Of Ligands By EXponential Enrichment (SELEX)TargetsSmall MoleculesProteinsMacromoleculesIn Vivo Diagnostic ApplicationsTherapeutic ApplicationsSpecificitySynthesizedProcessing ConditionsImmunogenicitySizeNucleotides (nt)Nucleic Acid LibrariesRandomized RegionsPrimer SitesSelection Process ComplicationsBioinformatics Approaches
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Pan, W., Xin, P., Patrick, S., Dean, S., Keating, C., Clawson, G. Primer-Free Aptamer Selection Using A Random DNA Library. J. Vis. Exp. (41), e2039, doi:10.3791/2039 (2010).
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