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May 18, 2010
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我々は、脳室周囲白質軟化症（PVL）、脳室周囲白質病変を特徴と未熟児で優勢な脳損傷のマウスモデルを確立した。全身感染症有/無低酸素/虚血は、PVLの主な原因です。リポ多糖注入なし/付き片側頸動脈結紮及び低酸素曝露がP6マウスのPVL様病変を作成します。
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Shen, Y., Plane, J. M., Deng, W. Mouse Models of Periventricular Leukomalacia. J. Vis. Exp. (39), e1951, doi:10.3791/1951 (2010).
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