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Primer Extension Capture: Targeted Sequence Retrieval from Heavily Degraded DNA Sources
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September 03, 2009
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Targeted DNA Sequence RetrievalHeavily Degraded DNA SourcesMicrobial DNA ContaminationAncient BonesSample Destruction ReductionSequencing Demands ReductionDirect PCRShotgun SequencingComplete Mitochondrial DNA (mtDNA) GenomesNeandertalsGeographic RangeMtDNA Genetic DiversityLate NeandertalsContemporary Modern HumansEffective Population Size
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Briggs, A. W., Good, J. M., Green, R. E., Krause, J., Maricic, T., Stenzel, U., Pääbo, S. Primer Extension Capture: Targeted Sequence Retrieval from Heavily Degraded DNA Sources. J. Vis. Exp. (31), e1573, doi:10.3791/1573 (2009).
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