Mapping the Tumor Immune Landscape: An In-Depth Multiplex IHC Analysis Protocol

August 18, 2023

肿瘤微环境空间免疫细胞景观的多重免疫组织化学分析

使用机器学习算法 ImmuNet 检测免疫细胞的工作流程

Mark A. J. Gorris², Evgenia Martynova*^1,3, Mark W. D. Sweep*^1,4, Iris A. E. van der Hoorn⁵, Shabaz Sultan³, Mike J. D. E. Claassens, Lieke L. van der Woude^2,6, Kiek Verrijp^2,6, Carl G. Figdor³, Johannes Textor³, I. Jolanda M. de Vries

¹Department of Medical BioSciences,Radboudumc, ²Division of Immunotherapy, Oncode Institute,Radboudumc, ³Data Science, Institute for Computing and Information Sciences,Radboud University, ⁴Department of Medical Oncology,Radboudumc, ⁵Department of Pulmonary Diseases,Radboudumc, ⁶Department of Pathology,Radboudumc

Summary

该方案详细描述了如何使用多重免疫组织化学对肿瘤微环境进行免疫细胞表征。

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