Journal
/
Neurosciences
/
Whole-Brain 3D Activation and Functional Connectivity Mapping in Mice using Transcranial Functional Ultrasound Imaging
Journal JoVE
Neurosciences
This content is Free Access.
Journal JoVE Neurosciences
Whole-Brain 3D Activation and Functional Connectivity Mapping in Mice using Transcranial Functional Ultrasound Imaging

Whole-Brain 3D Activation and Functional Connectivity Mapping in Mice using Transcranial Functional Ultrasound Imaging

8,735 Views

•

11:57 min

•

February 24, 2021

DOI:

10.3791/62267-v

DOI:
10.3791/62267-v

•

11:57 min
February 24, 2021

•

63 Views
, , , , , , , , , , ,
1Physics for Medicine Paris, ESPCI Paris, INSERM, CNRS,PSL Research University, 2Institute of Psychiatry and Neurosciences of Paris, INSERM U1266,Université de Paris, 3Iconeus, 4Department of Pharmacology and Toxicology,Jena University Hospital – Friedrich Schiller University Jena

Summary

Automatically generated

This protocol describes the quantification of volumetric cerebral hemodynamic variations in the mouse brain using functional ultrasound (fUS). Procedures for 3D functional activation map following sensory stimulation as well as resting-state functional connectivity are provided as illustrative examples, in anesthetized and awake mice.

Explore More Videos

Functional UltrasoundTranscranialWhole-brain3D ActivationFunctional ConnectivityMiceAnesthetizedAwakeNeuroimagingCerebral Blood VolumePlane Wave ImagingFMRIPortabilityHead FixationStereotactic FrameDental CementHead PlateAnesthesia

Read Article

Cite this Article

Bertolo, A., Nouhoum, M., Cazzanelli, S., Ferrier, J., Mariani, J., Kliewer, A., Belliard, B., Osmanski, B., Deffieux, T., Pezet, S., Lenkei, Z., Tanter, M. Whole-Brain 3D Activation and Functional Connectivity Mapping in Mice using Transcranial Functional Ultrasound Imaging. J. Vis. Exp. (168), e62267, doi:10.3791/62267 (2021).

Download .ris file

Copy

Share Video

.

Copy