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Implantation of Combined Telemetric ECG and Blood Pressure Transmitters to Determine Spontaneous Baroreflex Sensitivity in Conscious Mice
Journal JoVE
Médecine
This content is Free Access.
Journal JoVE Médecine
Implantation of Combined Telemetric ECG and Blood Pressure Transmitters to Determine Spontaneous Baroreflex Sensitivity in Conscious Mice

Implantation of Combined Telemetric ECG and Blood Pressure Transmitters to Determine Spontaneous Baroreflex Sensitivity in Conscious Mice

DOI:

09:56 min

February 14, 2021

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Chapitres

  • 00:05Introduction
  • 01:34Dissection of the Left Common Carotid
  • 04:09Cannulation of the Left Common Carotid Artery
  • 05:11Placement of the Telemetry Device Body and ECG Leads
  • 07:29Results: Analysis of BRS Using the Sequence Method on Simultaneous Telemetric ECG and BP Recordings
  • 08:58Conclusion

Summary

Traduction automatique

The baroreflex is a heart-rate regulation mechanism by the autonomic nervous system in response to blood-pressure changes. We describe a surgical technique to implant telemetry transmitters for continuous and simultaneous measurement of electrocardiogram and blood pressure in mice. This can determine spontaneous baroreflex sensitivity, an important prognostic marker for cardiovascular disease.

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