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Rotasyonel İvmeye Dayalı Sıçanlarda Diffüz Aksonal Beyin Hasarıİn İndüksiyonu
Journal JoVE
Neurosciences
Author Produced
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Journal JoVE Neurosciences
Induction of Diffuse Axonal Brain Injury in Rats Based on Rotational Acceleration
DOI:

06:14 min

May 09, 2020

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Chapitres

  • 00:04Introduction
  • 00:45Preparing Rats for the Experimental Procedure
  • 01:11Procedure of Induction Diffuse Axonal Brain Injury
  • 01:54Measurement of Rotational Kinematics, Biomechanical Parameters
  • 02:32Evaluation of Neurological Severity Score after 48 hours
  • 03:08Brain Collection for Histological Examination after 48 hours
  • 04:02Immunohistochemical Staining
  • 04:16Résultats
  • 05:22Conclusion

Summary

Traduction automatique

Bu protokol, kafatası kırıkları veya çürükler olmadan yaygın beyaz madde hasarına neden olan güvenilir, kolay ve tekrarlanabilir bir kemirgen beyin diffüz aksonal yaralanma (DAI) modelini doğrular.

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