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Development of a Larval Zebrafish Infection Model for Clostridioides difficile
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Development of a Larval Zebrafish Infection Model for Clostridioides difficile
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09:13 min
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February 14, 2020
DOI:
1Division of Cellular and Molecular Neurobiology, Zoological Institute,Technische Universität Braunschweig, 2Department of Molecular Biotechnology,Turkish-German University, 3Institut für Mikrobiologie,Technische Universität Braunschweig, 4Braunschweig Integrated Centre of Systems Biology, 5Helmholtz Centre for Infection Research
Summary
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Presented here is a safe and effective method to infect zebrafish larvae with fluorescently labeled anaerobic C. difficile by microinjection and noninvasive microgavage.
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Li, J., Ünal, C. M., Namikawa, K., Steinert, M., Köster, R. W. Development of a Larval Zebrafish Infection Model for Clostridioides difficile. J. Vis. Exp. (156), e60793, doi:10.3791/60793 (2020).
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