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Hybrid Microdrive System with Recoverable Opto-Silicon Probe and Tetrode for Dual-Site High Density Recording in Freely Moving Mice
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Hybrid Microdrive System with Recoverable Opto-Silicon Probe and Tetrode for Dual-Site High Density Recording in Freely Moving Mice
Chapitres
- 00:04Titre
- 00:54Microdrive Array Parts and Microdrive Screw Preparation
- 02:33Shuttle Preparation
- 03:08Optorode Preparation
- 06:43Results: Representative Simultaneous Tetrode/Silicon-Probe Stimulation and Recording
- 08:08Conclusion
This protocol describes the construction of a hybrid microdrive array that allows implantation of nine independently adjustable tetrodes and one adjustable opto-silicon probe in two brain regions in freely moving mice. Also demonstrated is a method for safely recovering and reusing the opto-silicon probe for multiple purposes.
