/
/
Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils
Un abonnement à JoVE est nécessaire pour voir ce contenu. Connectez-vous ou commencez votre essai gratuit.
Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils
10,590 Views
•
07:15 min
•
January 21, 2020
DOI:
Summary
Automatically generated
This article presents a protocol for establishing a ligature-induced model of murine periodontitis involving multiple maxillary molars, resulting in larger areas of the involved gingival tissue and bone for subsequent analysis as well as reduced animal usage. A technique to assess oral neutrophils in a manner analogous to human subjects is also described.
Read Article
Cite this Article
Chadwick, J. W., Glogauer, M. Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils. J. Vis. Exp. (155), e59667, doi:10.3791/59667 (2020).
Copy