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Fabrication of Amyloid-β-Secreting Alginate Microbeads for Use in Modelling Alzheimer’s Disease
Chapitres
- 00:04Titre
- 01:02Setting Up the Encapsulation System
- 02:16Microbeads Fabrication
- 04:10Testing and Use of Microbeads
- 04:57Results: Testing of Amyloid–Secreting
- 06:31Conclusion
This protocol illustrates a cell encapsulation method by rapid physical gelation of alginate to immobilize cells. Obtained microbeads allow controlled and sustained secretion of amyloid-β over time and can be used to study the effects of secreted amyloid-β in in vitro and in vivo models.
