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爆炸性神经损伤对压生啮鼠中脑动脉的影响
Journal JoVE
Neurosciences
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Journal JoVE Neurosciences
Effects of Blast-induced Neurotrauma on Pressurized Rodent Middle Cerebral Arteries
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爆炸性神经损伤对压生啮鼠中脑动脉的影响

6,883 Views

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08:21 min

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April 01, 2019

DOI:

10.3791/58792-v

DOI:
10.3791/58792-v

•

08:21 min
April 01, 2019

•

3 Views
, , , , ,
1Charles R. Allen Research Laboratories, Department of Anesthesiology,University of Texas Medical Branch, 2The Moody Project for Translational Traumatic Brain Injury Research,University of Texas Medical Branch

Summary

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在这里, 我们提出了一个协议来描述的方法, 在一次爆炸创伤性脑损伤 (bTBI) 后, 使用隔离, 加压, 啮齿类动物中脑动脉 (MCA) 段的体外血管反应性测定。bTBI 感应是使用激波管 (也称为高级爆破模拟器 (ABS) 装置) 完成的。

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Cite this Article

Rodriguez, U. A., Zeng, Y., Parsley, M. A., Hawkins, B. E., Prough, D. S., DeWitt, D. S. Effects of Blast-induced Neurotrauma on Pressurized Rodent Middle Cerebral Arteries. J. Vis. Exp. (146), e58792, doi:10.3791/58792 (2019).

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