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Пробоподготовки для анализа Endopeptidomic в цереброспинальной жидкости человека
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Neurosciences
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Journal JoVE Neurosciences
Sample Preparation for Endopeptidomic Analysis in Human Cerebrospinal Fluid
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Пробоподготовки для анализа Endopeptidomic в цереброспинальной жидкости человека

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10:23 min

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December 04, 2017

DOI:

10.3791/56244-v

DOI:
10.3791/56244-v

•

10:23 min
December 04, 2017

•

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1Inst. of Neuroscience and Physiology, Dept. of Psychiatry and Neurochemistry,Sahlgrenska Academy at University of Gothenburg, 2Clinical Neurochemistry Laboratory,Sahlgrenska University Hospital, 3Department of Molecular Neuroscience,UCL Institute of Neurology

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Endopeptidomic AnalysisCerebrospinal FluidSample PreparationLC-MSPeptide Pre-fractionationEndogenous PeptidesBiomarkersNeurodegenerative DisordersMWCO FiltrationHigh-pH Reverse Phase HPLCMass Spectrometry

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Hansson, K. T., Skillbäck, T., Pernevik, E., Holmén-Larsson, J., Brinkmalm, G., Blennow, K., Zetterberg, H., Gobom, J. Sample Preparation for Endopeptidomic Analysis in Human Cerebrospinal Fluid. J. Vis. Exp. (130), e56244, doi:10.3791/56244 (2017).

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