We provide simple and robust protocols for processing biopsy material of various species, embryos of biomedical model organisms and samples of other organic tissues in order to permit digital volume data generation with the high-resolution episcopic microscopy method.
Geyer, S. H., Maurer-Gesek, B., Reissig, L. F., Weninger, W. J. High-resolution Episcopic Microscopy (HREM) - Simple and Robust Protocols for Processing and Visualizing Organic Materials. J. Vis. Exp. (125), e56071, doi:10.3791/56071 (2017).