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Neural Activity Propagation in an Unfolded Hippocampal Preparation with a Penetrating Micro-electrode Array
Journal JoVE
Neurosciences
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Journal JoVE Neurosciences
Neural Activity Propagation in an Unfolded Hippocampal Preparation with a Penetrating Micro-electrode Array

Neural Activity Propagation in an Unfolded Hippocampal Preparation with a Penetrating Micro-electrode Array

DOI:

09:48 min

March 27, 2015

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Chapitres

  • 00:05Titre
  • 02:15Surgical Procedure for the Intact Hippocampus Preparation
  • 05:08Record the Unfolded Hippocampus on PMEA
  • 07:56Results: Data Recorded by the PMEA from an Unfolded Hippocampus
  • 09:09Conclusion

Summary

Traduction automatique

We have developed an in vitro unfolded hippocampus which preserves CA1-CA3 array of neurons. Combined with the penetrating micro-electrode array, neural activity can be monitored in both the longitudinal and transverse orientations. This method provides advantages over hippocampal slice preparations as the propagation in the entire hippocampus can be recorded simultaneously.

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