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Neural Activity Propagation in an Unfolded Hippocampal Preparation with a Penetrating Micro-electrode Array
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Neural Activity Propagation in an Unfolded Hippocampal Preparation with a Penetrating Micro-electrode Array
Kapitel
- 00:05Titel
- 02:15Surgical Procedure for the Intact Hippocampus Preparation
- 05:08Record the Unfolded Hippocampus on PMEA
- 07:56Results: Data Recorded by the PMEA from an Unfolded Hippocampus
- 09:09Conclusion
We have developed an in vitro unfolded hippocampus which preserves CA1-CA3 array of neurons. Combined with the penetrating micro-electrode array, neural activity can be monitored in both the longitudinal and transverse orientations. This method provides advantages over hippocampal slice preparations as the propagation in the entire hippocampus can be recorded simultaneously.
