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Myocardial Infarction and Functional Outcome Assessment in Pigs
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April 25, 2014
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This protocol describes the porcine myocardial infarction (MI) model using a 90 min closed-chest coronary balloon occlusion of the left anterior descending artery (LAD), followed by reperfusion. Furthermore, the protocol for several outcome parameters, such as cardiac function, hemodynamics, microvascular resistance, and infarct size, are also presented.
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Koudstaal, S., Jansen of Lorkeers, S. J., Gho, J. M., van Hout, G. P., Jansen, M. S., Gründeman, P. F., Pasterkamp, G., Doevendans, P. A., Hoefer, I. E., Chamuleau, S. A. Myocardial Infarction and Functional Outcome Assessment in Pigs. J. Vis. Exp. (86), e51269, doi:10.3791/51269 (2014).
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