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Myocardial Infarction and Functional Outcome Assessment in Pigs
JoVE 杂志
医学
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JoVE 杂志 医学
Myocardial Infarction and Functional Outcome Assessment in Pigs

Myocardial Infarction and Functional Outcome Assessment in Pigs

27,325 Views

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12:03 min

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April 25, 2014

DOI:

10.3791/51269-v

DOI:
10.3791/51269-v

•

12:03 min
April 25, 2014

•

13 Views
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1Department of Cardiology, Division Heart and Lungs,University Medical Center Utrecht, 2Interuniversity Cardiology Institute of the Netherlands

Summary

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This protocol describes the porcine myocardial infarction (MI) model using a 90 min closed-chest coronary balloon occlusion of the left anterior descending artery (LAD), followed by reperfusion. Furthermore, the protocol for several outcome parameters, such as cardiac function, hemodynamics, microvascular resistance, and infarct size, are also presented.

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Cite this Article

Koudstaal, S., Jansen of Lorkeers, S. J., Gho, J. M., van Hout, G. P., Jansen, M. S., Gründeman, P. F., Pasterkamp, G., Doevendans, P. A., Hoefer, I. E., Chamuleau, S. A. Myocardial Infarction and Functional Outcome Assessment in Pigs. J. Vis. Exp. (86), e51269, doi:10.3791/51269 (2014).

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